The article investigates the program-target method of management in the field of budget financing as one of the effective tools for the implementation of economic and social policy of the state. The analysis of interpretations of program-target management within which absence of unambiguous definition of this phenomenon is shown is carried out. Statistical data on budget financing of special federal programs, in particular in the direction of «Development of high technologies» are considered. Analyzed special federal programs «Research and development on priority directions of development of scientific-technological complex of Russia» 2007–2013 and 2014–2020 shows the existence of differences in their implementation, such as the kind supported by research, the volume of attracted extra-budgetary co-financing, method of formation of subjects. It was noted that during the implementation of the current special federal programs there are such negative phenomena as the absence of real mechanisms for the transfer of science into national programs implemented by other ministries, reducing the efficiency of the mechanism of public-private partnerships and the risks of formation of subjects «under the artist» without examination of the proper quality.

The review of domestic and foreign publications presents successful practices of corporate venture investment, which allow to clarify sustainability criteria and requirements for achieving stable functioning of corporate funds. It is shown that the coherence of the fund’s goals with the goals of the parent company, continuity of operation, continuity in relation to strategy, investment focus and the main team, as well as financial stability, which allows us to be a stable partner to portfolio companies throughout their entire life cycle, are of fundamental importance. It is emphasized that corporate venture investments are not an instrument of financial speculation, and the parent company needs the created venture fund, first, as an instrument for search, development, transfer of technologies, products and customers. The main differences between corporate and so-called independent venture capital funds, reflecting various goals, areas of activity, sources of financing, legal status, management remuneration systems and accountability, are examined.

Examines approaches to the development of human potential in the field of science in the modern scientific and technological development and modernization of the system of higher education based on a system of professional qualifications in the field of research, development and higher education. The article presents organizational models of preparation for research, scientific and expert, scientific and entrepreneurial (innovative), scientific and pedagogical activities in the field of science. The article describes the practice of organizing research master’s programs and training in the field of science on the example of programs of academic institutions, University programs, network programs with corporate research programs of state corporations, programs of specialized school scientific and technological education.

Within the framework of the priority national project «Science», as well as «Strategy of scientific and technological development of the Russian Federation», the country’s leadership has set tasks for medical science and health care that require the provision of preventive orientation of medical activity, the transition from disease treatment technologies to health-saving technologies. The solution of these tasks will require a paradigm shift in the field of public health, ensuring the attitude to health as an individual value of public importance, strengthening the corps of heads of health authorities and organizations, highly qualified personnel trained using the system of state scientific certification.

The purpose of the article is to show that there is a problem of displacement of knowledge and technologies related to health and its conservation from the scientific specialty «Public health and health care». Analysis of 277 dissertations with a time lag of 20 years showed that in fact there was a shift in the research interest of applicants «organizational» academic degree to the boundaries of their existing clinical specialty. The most frequent subject of dissertations in this specialty is the disease and diagnostic and treatment technologies. This problem can be described as «medicalization» of the managerial scientific specialty, which in the future may lead to a shortage of qualified managerial personnel capable of achieving the goals currently implemented in Russia’s state programs and strategies.

The purpose of the article is to outline the main provisions of the methodology for managing cognitive factors of production. It is shown that the processes of industrial re-industrialization, known as Industry 4.0, have led to the emergence of a new type of production resources –  cognitive factors of production. The essence of the concept of “cognitive factors of production” is determined, a structural diagram of the methodology of managing cognitive factors of production is presented. Based on the methods of system analysis, an organizational and economic management model is developed and a mechanism for integration into the general control loop of an industrial enterprise is proposed. In conclusion, conclusions are drawn about the possibility of applying the methodology of managing cognitive factors of production in a knowledge-based economy.

Based on the analysis of existing regulatory legal acts in the field of regulating the research activities of the member countries of the Eurasian Economic Union (EAEU), a conclusion was made about their similarity and the possibility of starting the operation of the single market of services (SMS) of research without adopting additional legal acts. A comparison of the sources of financing of science of the EAEU member countries with the average and best indicators in the world has been made. The average costs for the EAEU member country amounted to 0,43% of the gross domestic product (GDP) were 1,7% in the world (4 times more). In the EAEU, more research is carried out by public sector scientific organizations (31,8% in EAEU, 12,8% in the world), and less research is performed by the business sector. Proposals for the development of the EAEU SMS for the research, including the creation of the Science Fund and the Innovation Fund, the creation of an information resource on the websites of national regulators in the field of scientific activity, etc., have been made.